Find out how domperidone treats feeling sick (nausea) and vomiting, and how to take it. NHS medicines information on domperidone – what it's used for, side effects, dosage and who can take it. Mechanism of Action: Domperidone is a dopamine antagonist with antiemetic properties. Its effect may be attributed to a combination of peripheral (gastrokinetic) effects and antagonism of dopamine receptors in the chemoreceptor trigger zone (located in the area postrema). Domperidone should be taken 15-30 minutes before meals and, if necessary, before retiring.The usual recommended oral dose of Domperidone is as follows: Adults: 10-20 mg (1-2 tablet or 10-20 ml suspension), every 6-8 hours daily. The maximum dose of Domperidone is 80 mg daily. It is used to treat stomach-related issues, such as nausea and vomiting, as well as stomach pain and discomfort caused by decreased movement of the stomach and upper gastrointestinal (GI) tract. It is also used to boost breastmilk supply. Domperidone works by blocking dopamine receptors in the gut. Domperidone is used as immunotherapy to treat leishmania in dogs. [51] Domperidone is a drug that has been prescribed to increase breast milk supply. Learn more about it, if it works, and if it's safe to use. Each 5mL contains Domperidone 5mg. Buy Domperidone 5mg/5mL Suspension 60mL [PRESCRIPTION REQUIRED] online at Watsons Philippines. Get the best deals for VOMETA Domperidone 5mg/5mL Suspension 60mL [PRESCRIPTION REQUIRED]. Domperidone is a prescription medicine that helps reduce nausea and vomiting by improving stomach and intestinal motility. It is commonly used for symptoms linked to delayed gastric emptying, such as indigestion, bloating, and gastroesophageal reflux disease (GERD). Domperidone is a medicine that increases the movements or contractions of the stomach and bowel. Domperidone is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease. Domperidone is to be given only by or under the immediate supervision of your doctor. Domperidone is not an FDA-approved drug for any indication, or use, in humans. Domperidone is approved in some countries, but not in the U.S., to treat certain gastrointestinal disorders.